منابع مشابه
Calcium sparks.
The calcium ion (Ca(2+)) is the simplest and most versatile intracellular messenger known. The discovery of Ca(2+) sparks and a related family of elementary Ca(2+) signaling events has revealed fundamental principles of the Ca(2+) signaling system. A newly appreciated "digital" subsystem consisting of brief, high Ca(2+) concentration over short distances (nanometers to microns) comingles with a...
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متن کاملSparks of Frog Skeletal Muscle
An algorithm for the calculation of Ca 2 1 release flux underlying Ca 2 1 sparks (Blatter, L.A., J. Hüser, and E. Ríos. 1997. Proc. Natl. Acad. Sci. USA. 94:4176–4181) was modified and applied to sparks obtained by confocal microscopy in single frog skeletal muscle fibers, which were voltage clamped in a two-Vaseline gap chamber or permeabilized and immersed in fluo-3–containing internal soluti...
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We question whether creativity requires functions exclusive to the human mind or it can rather be obtained by the mere performance of well-defined prescribed operations. The natural thinking process involves a complexity of sensory inputs, psychological factors, cognitive background, social rules and constraints which interfere (constructively and at times, destructively) with the results and e...
متن کاملPerspectives on Ca2+ Sparks
The purpose of the Perspectives in General Physiology is to provide a forum where scientific uncertainties or controversies can be discussed in an authoritative, yet open manner. The Perspectives are solicited by the editors—often based on recommendations by the advisory editors or members of the editorial board, who may be asked to coordinate the process. To frame the issue, two or more expert...
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ژورنال
عنوان ژورنال: Nature
سال: 2003
ISSN: 0028-0836,1476-4687
DOI: 10.1038/425908a